1. Signaling Pathways
  2. Anti-infection
  3. Parasite

Parasite

Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N9320
    13,21-Dihydroeurycomanone
    Inhibitor 98.11%
    13,21-Dihydroeurycomanone, a natural compound isolated from Eurycoma longifolia root, possesses anti-parasite activity for Plasmodium falciparum and Toxoplasma gondii.
    13,21-Dihydroeurycomanone
  • HY-B1056
    Procodazole
    Inhibitor 99.73%
    Procodazole is an orally active enhancer and a non-specific active immune protector against viral and bacterial infections. Procodazole also exhibits antiparasitic activity. In addition, Procodazole is a carbonic anhydrase inhibitor with antitumor activity.
    Procodazole
  • HY-U00295
    Melarsonyl
    Inhibitor
    Melarsonyl (Melarsonic acid) is an anthelmintic agent which can inhibit parasite potently.
    Melarsonyl
  • HY-153021
    NMT-IN-1
    Inhibitor ≥98.0%
    NMT-IN-1 (compound 9) is a potent N-Myristoyltransferase (NMT) Inhibitor with IC50 values of 31 and 66 μM for TbNMT and hNMT, respectively. NMT-IN-1 can be used in research of african trypanosomiasis.
    NMT-IN-1
  • HY-135648
    PfDHODH-IN-1
    Inhibitor 99.85%
    PfDHODH-IN-1 is an analogue of the active metabolite of Leflunomide. PfDHODH-IN-1 is a Plasmodium falciparum dihydroorotate dehydrogenase (PfDHODH) inhibitor. PfDHODH-IN-1 has antimalarial activity.
    PfDHODH-IN-1
  • HY-N0924A
    (±)-Stylopine hydrochloride
    99.66%
    (±)-Stylopine (Tetrahydrocoptisine) hydrochloride is an alkaloid compound originally isolated from Corydalis tubers that exhibits anti-inflammatory and anti-parasitic activities.
    (±)-Stylopine hydrochloride
  • HY-B1244S
    Dimetridazole-d3
    Inhibitor 99.87%
    Dimetridazole-d3 is a deuterium labeled Dimetridazole. Dmetridazole, a nitroimidazole-based antibiotic, combats protozoan infections[1].
    Dimetridazole-d<sub>3</sub>
  • HY-121002
    Alstonine
    Inhibitor
    Alstonine is a major indole alkaloid compound of a plant-based remedy. Alstonine has antipsychotic, anxiolytic, anticancer and antimalarial properties.
    Alstonine
  • HY-B0744C
    L-Eflornithine
    L-Eflornithine (L-DFMO) is an enantiomer of Eflornithine. L-Eflornithine is an irreversible ornithine decarboxylase (ODC) inhibitor with a KD of 1.3±0.3 µM, and a Kinact of 0.15±0.03 min-1.
    L-Eflornithine
  • HY-117025
    Manzamine A
    Inhibitor
    Manzamine A, an orally active beta-carboline alkaloid, inhibits specifically GSK-3β and CDK-5 with IC50s of 10.2 μM and 1.5 μM, respectively. Manzamine A targets vacuolar ATPases and inhibits autophagy in pancreatic cancer cells. Manzamine A has antimalarial and anticancer activities. Manzamine A also shows potent activity against HSV-1.
    Manzamine A
  • HY-119819
    Psicofuranine
    Inhibitor ≥98.0%
    Psicofuramine a nucleoside antibiotic and has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine also specifically inhibits GMP synthase, and interrupts parasite growth. Psicofuranine exhibits a dose-dependent inhibition of P. falciparum growth.
    Psicofuranine
  • HY-W019829
    Polyphyllin C
    Inhibitor
    Polyphyllin C (compound 2) is a spirostanol saponin. Polyphyllin C exhibits mild (IC50=36.87 µM) activities against the tyrosinase and moderate (IC50=1.59 µg/mL) antileishmanial activities.
    Polyphyllin C
  • HY-B2186
    Piperazine adipate
    Inhibitor ≥98.0%
    Piperazine adipate is a potent broad spectrum anthelmintic against many common worm infections in mammals.
    Piperazine adipate
  • HY-121495
    BKI-1369
    Inhibitor 98.77%
    BKI-1369 is a bumped kinase inhibitor (BKI). BKI-1369 increases human Ether-a-go-go-related gene (hERG)-inhibitory activity with an IC50 of 1.52 μM. BKI-1369 reduces the parasite burden and diseases severity in the gnotobiotic pig model. BKI-1369 has been well characterized for potency, stability, metabolism, toxicity, pharmacokinetics and is potent against C. parvum in infected mice and calves.
    BKI-1369
  • HY-B1934S1
    Methyl stearate-d35
    Inhibitor
    Methyl stearate-d35 is the deuterium labeled Methyl stearate. Methyl stearate, isolated from Rheum palmatum L. is a compopent of of soybean and rapeseed biodiesels[1].
    Methyl stearate-d<sub>35</sub>
  • HY-B0357S
    Diclazuril-d4
    Inhibitor ≥98.0%
    Diclazuril-d4 is deuterium labeled Diclazuril. Diclazuril (R-64433), a benzeneacetonitrile derivative, is a potent and orally active anticoccidial agent. Diclazuril can be used for the research of certain infectious and parasitic diseases, including coccidiosis, acute toxoplasmosis, equine protozoal pyoencephalitis (EPM) et.al[1][2].
    Diclazuril-d<sub>4</sub>
  • HY-107771
    Fluensulfone
    Inhibitor 99.31%
    Fluensulfone is a new nematicide for chemical control of plant parasitic nematodes.
    Fluensulfone
  • HY-N8471
    Niazinin
    Inhibitor 99.94%
    Niazinin is a thiocarbamate glycoside with antileishmanial activities, with an IC50 value of 5.25 μM. Niazinin also shows a binding affinity with the target protein 3CL protease. Niazinin has promising leishmanicidal, anti-inflammatory and anti-pyretic activity.
    Niazinin
  • HY-109077
    Tigolaner
    Inhibitor 98.53%
    Tigolaner (BAY-1272858) acts on γ-aminobutyric acid (GABA) and glutamate-gated chloride channels. Tigolaner has antiparasitic activity.
    Tigolaner
  • HY-107814S
    Nicarbazin-d8
    Inhibitor 99.99%
    Nicarbazin-d8 is deuterium labeled Nicarbazin. Nicarbazin is an effective anticoccidial agent for chickens[1].
    Nicarbazin-d<sub>8</sub>

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